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Acknowledgements This work was supported in part by grants AI 048,079, AI 072,648, and AT004332 from the National Institutes of Health, the Alliance for Lupus Research, and the Central New York Community Foundation

Techniques such as enzyme assays and mass spectrometry are used to measure NADPH concentrations and assess how shifts in NADPH production impact cellular functions

The skin in this area is very thin, with blood vessels close to the surface

Mavropoulos A, Zafiriou E, Simopoulou T, Brotis AG, Liaskos C, Roussaki-Schulze A, Katsiari CG, Bogdanos DP, Sakkas LI

Cell Biol 8 (10) (2007) 813824

Strikingly, selective deletion of EAAT2 in spinal cord astrocytes is sufficient to induce motor neuron degeneration and impairs motor learning and coordination in mice [391]