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For sonosensitizer accumulation, ie, protoporphyrin IX, the metabolite of 5-ALA, an optimal pre-incubation period of 5-ALA with tumor cells before ultrasonic exposure was found at 4 h

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2) is widely accepted, and several inducers of this type of erythrocyte death have been described, including the antiinflammatory compounds Bay 11-7082, parthenolide, and dimethyl fumarate [113], H 2 O 2 [114], the food additive E407a (semi-refined carrageenan) [115], and the tricyclic antidepressant desipramine [116]