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A recent meta-analysis of 12 observational studies found that higher dietary intake of vitamin B 12 was associated with a 23% lower risk of depression compared to lower intakes, but stratifying the data revealed a significant protective association in females, not in males (99)

Subcutaneous injection, 1 to 2 times per week

These studies require decades-long commitment but provide irreplaceable evidence for transgenerational effects in human populations

Li et al., 2014b

Quantity: 1ml ampoule

When you have MTHFR gene mutations you lack the enzymes responsible for the conversion of folate that you eat into the active form 5-Methyltetrahydrofolate