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It is proposed that the dimeric KEAP1 captures NRF2 first through the ETGE motif, which has 100-fold more affinity to KEAP1, followed by DLG motif docking onto the other Kelch repeat domain

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doi: 10.1038/s41580-020-0230-3 3 ShekhovaE

Molecular cloning and characterization of Escherichia coli K12 ygjG gene

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Similarly, host-microbe interactions are based on a code that is far from being deciphered, highlighting the need to persist with a wet approach