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Small amounts can be found in the fruiting bodies of edible fungi and edible algae [38] and bacteria associated with plants [39]

The toxicity increased with the increase in the sulfadiazine concentration extracted by HF-LPME at different pH values, suggesting that the HF-LPME extracted concentration can be used to estimate the toxicity of sulfadiazine independent of the ambient pH, that was the concentrations of sulfadiazine in the test solutions measured by HF-LPME and the corresponding immobilization-concentration-response equation were used to calculate the immobilization ratio

GSK3 is a protein kinase specific to serine and threonine and plays a crucial role in the Wnt signaling pathway [138]

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