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10.1161/01.CIR.0000109496.82683.49 Circulation 165 ShimamuraM.SatoN.WaguriS.UchiyamaY.HayashiT.IidaH.et al (2006)

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It enhances the results of professional aesthetic treatments, making it a popular choice among dermatologists and aesthetic practitioners

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It was developed by Joseph Harding and colleagues at Washington State University and published in 2013