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doi: 10.1016/j.cyto.2023.156144 185 Sharifi-RadJRayessYERizkAASadakaCZgheibRZamWet al

The combination of the lysosome disruptor siramesine and the tyrosine kinase inhibitor lapatinib increased the expression of TF and reduced the expression of FPN1 in breast cancer cells, thereby promoting iron overload in the lysosome and ultimately inducing ferroptosis ( Ferroptosis could be induced by directly supplementing the cell's active iron pool to establish an iron overload state

Innate immunity and inflammation, two faces of the same biological coin The first line of immune defense against pathogens, before adaptive immunity (antibodies, T cell responses) develops, is called innate immunity

K., Ansay M
Jing, L

Giaccari A, Solini A, Frontoni S, Del Prato S
