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Sokolova, T

Preclinical in vitro and in vivo assays demonstrate that ALA modulates different pathways of oxidative stress and attenuates nociception in NP models of diabetic neuropathy, peripheral nerve constriction injury, and autoimmune encephalomyelitis mimicking multiple sclerosis-associated pain

Microglia: the metabolic checkpoint The decision of microglia to either support or prune neurons and synapses may be guided by a metabolic checkpoint. We postulate that microglia constantly assess the metabolic fitness of neighboring neurons by sensing specific metabolites released from dysfunctional cells