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Furthermore, it promotes the ROS-dependent E2F1-mediated degradation of HIF-1, which decreases VEGF expression [23]

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For instance, astragaloside IV, a natural compound extracted from Astragalus , showed neuroprotective effects through calcium-sensing-receptor-mediated apoptosis

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2.2 Identification and enrichment strategies A variety of chemical tools have been developed to investigate lysine lactylation at the proteomics level

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Some recent studies discovered that ACEI analogs play a role in regulating lipid metabolism

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