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If this pattern holds for retatrutide, nasal delivery could offer a GI-tolerability advantage for individuals who respond well to the central appetite effects but struggle with peripheral GI symptoms
Vitamin D3 (cholecalciferol) is a fat-soluble vitamin synthesized in the skin when exposed to sunlight
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Moreover, two studies from the same group demonstrated increased duodenal permeability, assessed by CLE, in IBS patients upon perfusion of diluted food antigens (49, 50)
