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It binds cardiolipin, the unique lipid that organizes the inner mitochondrial membrane

Drosophila studies showed 11-16% extension Telomerase activation: In vitro studies confirmed hTERT upregulation in human fetal fibroblasts and pulmonary cells, with treated cells exceeding the Hayflick limit by approximately 10 additional population doublings Telomere elongation: Direct measurements showed statistically significant telomere lengthening in treated cells Cancer incidence: Long-term animal studies showed reduced spontaneous tumor formation, partially addressing the telomerase-cancer concern 2025 validation: An independent study confirmed telomere-lengthening effects across multiple human cell lines, representing the first significant non-Khavinson replication Key limitations: The evidence base is dominated by a single research group

Preserving bloodbrain barrier integrity in ischemic stroke: a review on MSCs-sEVs content and potential molecular targets

Iron import and storage proteins (DMT1, transferrin receptor, ferritin) are abnormally upregulated in ALS models, indicating that microglia and astrocytes may sequester excess iron and propagate oxidative stress [234]

Triglyceride content of the liver was found to decrease in a dose-dependent manner with increasing methionine ingestion

In experimental models of cerebral ischaemia, DSIP administration was associated with accelerated restoration of motor coordination and reduced neuronal damage, with proposed mechanisms involving stabilisation of neuronal membrane function and protection against excitotoxicity from excessive glutamate signalling