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IL-1 has been shown to directly induce catabolism in C2C12 derived myotubes, suggesting a direct causal relationship in cachexia [23]

Several studies on different hematological malignancy cells, including AML, CLL, ALL, MM have designated that nutlins affect wild-type p53 in transcription-dependent [728,729,730] or transcription-independent manners [731,732,733,734]

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When getting older, the body production of L-Carnitine will be decreased, leading to easy obesity