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J Pineal Res 60:383393
387,388,389 Oxidation-reduction modifications also participate in the regulation of AMPK activation, where Cys130 and Cys174 of AMPK can form disulfide bonds through oxidation, thereby impeding the binding of AMPK kinase to AMPK and subsequent AMPK activation
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It has been shown to reverse pathological expression of 70% of genes in a gene signature for metastasis-prone colon cancer and to shift gene expression in COPD lungs from destruction to healthy remodeling
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