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The trial dosed the first participants in late 2020 with the aim of using CRISPR to reduce the amount of disease-related protein, TTR, made by the liver

In this study, we resolved the cryo-EM structures of the MARV and EBOV polymerases at resolutions of 2.7 and 3.1 , respectively, and both structures adopt as an elongation state
Physiol Rev 95:377404

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