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As a model for physiological conditions the cancer cells were cultivated and treated with a 21% O 2 atmosphere, and as a model for hypoxic conditions the cancer cells were cultivated and treated with a 1% O 2 atmosphere

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Conclusions Over the past few years, significant progress has been made on the understanding of melanocyte biology and its underlying mechanism, opening up new research avenues for the discovery of novel melanogenesis inhibitors

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doi: 10.1016/0014-5793(94)00947-3 68 UrsiniF.MaiorinoM

Others may do it monthly or just prior to certain events (e.g