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ME/CFS lacks standardised diagnostic criteria owing to variations in both inclusion and exclusion criteria across different diagnostic guidelines, and furthermore, there are currently no effective treatments available

In general, each active site has a conserved sequence of amino acids for each specific binding site

At the molecular level, their phenolic hydroxyl groups readily donate hydrogen atoms to neutralize reactive oxygen and nitrogen species, forming relatively stable phenoxyl radicals through resonance delocalization across aromatic rings (9497)

Rights and permissions About this article Cite this article Nianiou-Obeidat, I., Madesis, P., Kissoudis, C

Supplementation to reach these levels can vary greatly between individuals due to several factors, therefore testing is essential in order to calculate the appropriate supplement amount