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After exposure to H 2 O 2 there was significantly more oxidized Bodipy-C11 in macrophages from healthy donors and individuals with active CD compared to untreated cells indicating increased lipid peroxidation (Fig

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Superoxide dismutase (SOD) is an enzyme that catalyzes the conversion of superoxide anions to hydrogen peroxide and oxygen, thereby preventing the formation of more reactive oxygen species

The significance of SerpinB2 expression by the macrophage subsets is not clearly understood

Altered cAMP distribution in AML12 cells treated with DMSO or Ceefourin-1 was also evaluated as above

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