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The precedent has been set

145,146 In one controlled trial, 198 airline passengers with moderate to high risk of venous thrombosis were given either pycnogenol, at 200 mg before and during a long flight (averaging 8 hours 15 minutes) plus 100 mg the next day, or placebo

It potentially supports weight management while improving overall metabolic health

They promote fat splitting and prevent fat storage in the liver

The most common way to prevent or fix a deficiency is by getting vitamin B12 shots