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He Z, Zhao Y, Rau MJ, Fitzpatrick JAJ, Sah R, Hu H, et al

It may protect against A toxicity and reduce inflammatory damage [120]

Van der Veen, J

Dickson R

doi: 10.1038/s41568-019-0205-x 17 KimGKoYT
Partial oxygenation results in a Hb conformational change that produces a dramatic increase in the rate of autoxidation and the affinity of Hb for the RBC membrane (Cao et al., Extracellular hemoglobin as a source for oxidative stress Extracellular Hb, whether originating from hemolysis of RBCs or the infusion of cell-free Hb-based blood substitutes, can be a major source for oxidative stress
