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Fractions for AEA and 2-AG measurement were obtained by eluting the columns with 9:1 (by volume) chloroform/methanol and then analszed by LCAPCIMS

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2024;12:e5606

It was a demonstration that the peptide field itself has evolved

The gut converts the other 20% of T4-T3

The model predicts synergistic efficacy for combination of AXT050 with sorafenib, cabozantinib, and rilotumumab but not synergistic potency We next used the calibrated and validated model to investigate the effect of the combination of AXT050 with other therapeutics targeting HGF/Met signaling pathway to predict synergy