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Shifts the balance of certain proteins inside cells toward survival signals and reduces activity of a protein involved in cell death, helping protect cells from dying off

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Conversely, manipulating these miRs can enhance CD38 expression via cell effectors ( 2.1.1.5 Immunomodulatory imide Drugs (IMiDs) IMiDs are key components of standard myeloma therapy, especially in combination with mAbs

A deficiency can occur for several reasons, such as pernicious anemia (a condition where the body cannot absorb vitamin B12 from the diet), certain medical conditions (e.g., Crohn's disease, celiac disease), surgical removal of part of the stomach or intestine, or strict vegetarian/vegan diets if not adequately supplemented

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Spermidine-spermine N 1 -acetyltransferase (SSAT) takes acetyl-CoA as a substrate to acetylate spermidine and spermine