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50 This finding not only strengthens the concept that oxidative stress indeed is not only the key factor in determining the degree of endothelial dysfunction but also that it impacts the prognosis of patients with established atherosclerosis
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Feb 1 2017;95(3):154-162
The first reported GPX4 inhibitor RSL3 covalently interacts with selenocysteine, the active site of GPX4, to inhibit enzymatic activity of GPX4, thus inducing ferroptosis
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