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doi: 10.1038/s41598-018-19669-4 279 MantC

Cagrilintide's half-life of approximately seven days allows for flexible dosing windows (administration can be delayed by 12 days without loss of efficacy), but missed doses beyond five days require restarting the titration schedule to avoid rebound nausea

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An increase in activated microglia has been observed in both PD patients and healthy older people, indicating that various triggers might induce a proinflammatory shift with age (57)

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