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At the cellular and subcellular levels, persistent oxidative stress damages RNA, DNA, pigments and proteins and causes the disintegration of membranes through lipid peroxidation, which eventually leads to de-compartmentation and cell death (Gill and Tuteja 2010
Neuroscience 39, 151170
Significant myelin and axonal damage have also been detected in HD (Di Paola et al., 2012) and may underlie the WM changes observed in this condition
Ibuprofen can affect the way platelets work and increase the effects of blood thinners
Flaws J
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