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Ammonia is toxic to the brain, with the potential to cause cerebral edema and herniation

10.3390/ijms21051846 116 YamazakiN.ShinoharaY.ShimaA.YamanakaY.TeradaH

Treatment with AR antagonist flutamide increased H 2 O 2 levels by approximately 2.4-fold and decreased MMP and ATP production in hepatocytes (120), which further demonstrates the important role of androgens/AR in regulating cellular oxidative stress levels

England and Ruhnke, 2020

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Cq values were processed according to Hellemans et al