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By favorably influencing the folate/methionine cycle and restricting methionine metabolism, MOTS-c induces a shift in cellular priorities from growth toward maintenance

2003 Jan;2(1):13-21

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HighDose Intravenous Vitamin C, a Promising MultiTargeting Agent in Cancer Therapy Source: BioMed Central / Journal of Experimental & Clinical Cancer Research Summary: This article reviews mechanistic evidence and early clinical trials of high-dose IV vitamin C in oncology, detailing how pharmacologic ascorbate may exert cytotoxic effects in tumor cells, while reviewing limitations and future directions