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The PEG-DSF-Cu/ZIF-8 exhibited desirable dispersity and high hydrolytic stability in normal physiological conditions (Fig

A reduction in expression of proteins like claudin-5 and Occludin involved in the formation of BBB TJs and various markers such as IL-8 and metalloproteinase 1 tissue inhibitor are related to increased BBB permeability, which have been observed in HD patients [114, 115]

Vitamins have excellent neuroprotective effects against the oxidative stress induced by metal and non-metals, and can protect against lead-induced neuronal apoptosis in rats (Ebrahimzadeh-Bideskan et al., 2016), aluminum-induced neuronal apoptosis in Nile perch (Khalil and Hussein, 2015), iron-induced oxidative stress in rat brain tissue (Ganie et al., 2014), and arsenic-related neurological damage in rats (Sarkozi et al., 2016)

Acetylcholinesterase inhibitors Dysfunction of brain cholinergic neurotransmission has been described in several patients diagnosed with ASD (Perry et al., 2001
When hepatic fibrosis is accompanied by a nodular or non-nodular regenerative response in the liver, it may be considered by some to represent cirrhosis

Stockstill et al., 2018
