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Biotechnol 42, 362366 (2024)

The increased incorporation of n3-PUFAs in membranes affects both the innate and adaptive immune responses, impairing the maturation of dendritic cells and the function of macrophages, as well as the polarization and activation of T and B cells (110112)

Biologic agents are usually injected either subcutaneously (under the skin) or intravenously (through a tube inserted into a vein)

Deniaud A, Sharaf el dein O, Maillier E, Poncet D, Kroemer G, Lemaire C, et al

32 The authors used selfadministered questionnaires including neuropathic pain scores, visual analog scale (to quantify pain), SF12 (to quantify overall health), UCLA activity scale (to quantify activity level), and the WOMAC (to quantify pain, stiffness, and physical function) as their outcome measures

This phenomenon indicates that the rise in cellular ROS level occurs about 2 h after NO buildup, which is in line with our earlier observations with erastin [9, 11, 45] and sulfasalazine [12]