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3D, E), indicating that combined loss of PHD2 and GSTP1 drives a coordinated, systems-level shift toward growth arrest and cell death that exceeds the effects of either perturbation alone, with potentially lethal consequences for cellular viability

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Following GSH treatment, the levels of POD in the GSH96 group were significantly higher than those in the GSH48 group and were also significantly higher than those in any of the other treatment groups

Membrane localized iridium (III) complex induces endoplasmic reticulum stress and mitochondria-mediated apoptosis in human cancer cells

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doi: 10.1371/journal.pone.0072069