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The magnified AFM images show the hexagonal tiles whose assembly scheme is illustrated in the middle panel

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Despite autophagy is once considered a non-selective process that mediated the bulk degradation of cytoplasmic components, current studies have demonstrated it can specifically target damaged organelles, such as mitochondria, ruptured lysosomes, peroxisomes, ER, lipid droplets (Levine and Kroemer, 2019)

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