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Another study showed that at 7,500 mg/day, there is a slight blood pressure-lowering effect.[ref] A 2021 study on adults prescribed to take choline (alpha-GPC) found a correlation between increased stroke risk and taking alpha-GPC

Effect of antioxidants on sperm quality parameters in subfertile men: a systematic review and network Meta-analysis of randomized controlled trials

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Interestingly, decreased concentration of L-carnitine was also found in the skeletal muscles of hypothyroid patients (215), suggesting that L-carnitine depletion in skeletal muscles may contribute to myopathy associated with either hypothyroidism or hyperthyroidism
