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Interestingly, the same Abdeg was shown to improve radioimaging by shortening the in vivo plasma half-life of a radioactively labeled, tumor-specific human IgG1 mAb in mice, resulting in reduced systemic exposure and thereby improving the imaging contrast in positron emission tomography [121]

10.1073/pnas.74.1.158 4 BensonA

Emerging trends in oral delivery of peptide and protein drugs

doi:10.3389/fmolb.2022.925700 Zhang Q, Liu J, Deng M ming, Tong R, Hou G

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This multi-pathway approach enables effects across diverse tissue types and may explain the enhanced healing outcomes observed in combination studies compared to single-peptide protocols