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Funding Open Access funding provided by Osaka University

Similarly, N-acetyl-serotonin activates TrkB/BDNF/CREB signaling in primary neurons to reduce oxidative stress and associated neuronal death (Al-Kuraishy & Al-Gareeb, 2020

High levels of free radicals may cause oxidative stress, which is associated with chronic diseases like heart disease, diabetes, and cancer

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Co-treatment of LY294002 or MK-2206 with AZD5363 attenuates AZD5363-induced increase in the level of phosphorylated AKT

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