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Many women with polycystic ovarian syndrome (PCOS) also have cortisol resistance [15]

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Estrogen also helps maintain collagen and joint lubrication, so as levels fall, many women notice increased morning stiffness, aching after routine activity, and a greater risk of tendon or ligament injury

Lancet 2:820, 1956

[PubMed: 15339744] 66

(15) At this stage, the person will have been likely treated with thyroid medications, so if they are receiving ideal treatment, their TSH, Free T3, and Free T4 numbers should be in a good range