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A genetic approach can be helpful in validating the target in cells, for example, showing that resistance mutations reside in that target gene or compensation of growth defect through overexpression of the target protein
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doi: 10.1074/jbc.M117.787176
Role of retinoid X receptors (RXRs) and dietary vitamin A in Alzheimers disease: evidence from clinicopathological and preclinical studies
Scientists are discovering new connections between the gut and brain, developing better tests for inflammation, and creating more targeted treatments
