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Given the plasticity of MCFs in response to the AT microenvironment, it is essential to characterize changes in protein expression under different metabolic stimuli to describe their metabolic-functional heterogeneity

McLaurin et al., 2021)

Nature 617 (7961), 443444

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Critically, AOD-9604 did not produce the metabolic side effects associated with full-length growth hormone, including no insulin resistance or glucose intolerance, no elevation of IGF-1 levels, no fluid retention or joint pain, and no cardiovascular parameter changes