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The most recent WHO report stated that there is limited empirical evidence for the benefit of applying the omega-6:omega-3 ratio or recommending a specific dietary LA:ALA ratio [66]

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(2010) focused on several candidates affected by PHYA or FIN219

doi: 10.1189/jlb.3RU0316-144R

Hemoglobinopathies Sickle cell disease SCD is caused by a point mutation in the Hb subunit chain and shows multiple clinical manifestations and early mortality, particularly if the individual is homozygous for the mutation or untreated (80)