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When they are open, tight junctions allow material to pass between cells

Pseudocholinesterase deficiency is most commonly diagnosed only after a patient experiences prolonged skeletal muscle blockade after a standard dose of succinylcholine or mivacurium are given (Andersson et al, 2019)

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Central activation of neurons This 6-year-old girl presents with early onset of secondary sexual characteristics (thelarche, pubarche) and vaginal bleeding accompanied by elevated gonadotropins and sex steroids

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