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Description
Synapsin is a pharmacist-compounded nasal spray combining Ginsenoside Rg3, Nicotinamide Riboside (Vitamin B3), and Methylcobalamin (Vitamin B12)

Deficiency can raise homocysteine and impair methionine recycling

Because not enough research has been done supporting its safety in these groups, the use of pine bark extract should be avoided
The current studys observation of elevated medium-chain acylcarnitines (C8, C10) contrasts with prior literature, representing a novel finding

10.1136/annrheumdis-2018-213299 Ann Rheum Dis

Perhaps not significantly for short-term, but careful study is needed
