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We refer to Supplementary Note 1 for more details on the cell-type dynamics and senescence in skeletal muscle

The frequency of immune cell subsets was assessed by staining 1 x 10 6 nucleated cells with CD45 (KO), CD56 (PC7), CD138 (APC) (both Beckman Coulter), CD14 (PerCP), CD19 (APC-H7), CD3 (V450) and CD16 (PE) (all BD Biosciences)

Patient #3 gained independent brow and eyelid motion, which he totally lacked prior to treatment

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this is the most common cause of vitamin B12 deficiency in the UK a lack of these vitamins in your diet this is uncommon, but can happen if you have a vegan diet and do not take vitamin B12 supplements or eat foods fortified with vitamin B12, follow a restrictive diet or have a generally poor diet for a long time medicine certain medicines, including anticonvulsants and proton pump inhibitors (PPIs), can affect how much of these vitamins your body absorbs Both vitamin B12 deficiency and folate deficiency are more common in older people, affecting around 1 in 10 people aged 75 or over and 1 in 20 people aged 65 to 74