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While 5-FU primarily exerts its cytotoxic effects by disrupting DNA synthesis and inducing oxidative stress that exceeds a cytotoxic threshold 27 , cancer cells often counteract this oxidative stress by upregulating antioxidant defenses, leading to therapy resistance 10

[DOI] [PubMed] [Google Scholar] 295.Ullah N, Khan FM, Mukhtiar M

In vivo analysis reported the role of BBB breakdown in initiating changes to transcriptional processes of the neurovascular network, further causing degenerative disorders like AD, psychological impairments, cognitive decline, and epilepsy [92]
Suh 2004)

Needless for further emphasis, ATP is by large one of the most important molecules for cancer cells

Glia as sculptors of synaptic plasticity
