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If MAD is correct, then the primary focus should be mainly in the management of microbial infections within and outside of the CNS, and secondarily in the treatment of downstream consequences, approaches that could be performed simultaneously

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Diffusivity metrics including mean, axial and radial diffusivity (MD, AD and RD, respectively), measure the degree of water diffusion across the myelinated axons in all directions (MD), parallel to the direction of the axons the (AD) or perpendicular (radial) to them (RD)

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10.1186/s12974-021-02295-9 139 ZhouC.TajimaN