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found in their study that in clear cell renal cell carcinoma (ccRCC) tumor cells, endogenous Gln metabolism might reduce the anti-tumor effectiveness of T cells by promoting the Treg cell response ( 2.1.4 Regulation of tumor cell redox homeostasis Gln regulates the redox status of cancer cells by influencing the production of mitochondrial ROS

James SJ, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O et al

This effect resulted in a potent inhibitory effect of AC on TNBC progression and metastasis

Hepatology 1996

Luminal contents can pass across the epithelial barrier via transcellular passive, active or endocytosis mechanisms, or via paracellular pathway

Mediterranean diet during pregnancy and infant neurodevelopment: a prospective birth cohort study