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Its most consistently documented mechanism involves VEGFR2 activation and Akt-eNOS signaling, promoting angiogenesis in connective tissue research models (Hsieh et al., Journal of Molecular Medicine, 2017, DOI: 10.1007/s00109-016-1488-y)
DOI: 10.3390/antibiotics15030251
Most experimental and clinical research uses ascorbic acid or its sodium salt, called sodium ascorbate
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Q.et al (2003)
In practical terms, the research-backed portion of the formula is the 300mg standardized extract, while the added root powder is better viewed as a supporting inclusion
