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Furthermore, recent cardiovascular outcome trials, such as EMPA-REG OUTCOME (BI 10773 [Empagliflozin] Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients), CANVAS (CANagliflozin cardioVascular Assessment Study), and DECLARE (Dapagliflozin Effect on Cardiovascular Events), have not reported any significant difference in NAF for patients on SGLT2 inhibitors (5254)

Milara J, Peir T, Serrano A, Guijarro R, Zaragoz C, Tenor H, Cortijo J (2014) Roflumilast N-oxide inhibits bronchial epithelial to mesenchymal transition induced by cigarette smoke in smokers with COPD

dietary and nutritional supplements for general health and wellbeing