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Lipid peroxidation-derived electrophiles modulate the mitogen-activated protein kinase (MAPK) pathway via JNK and ERK signaling, linking oxidative stress to proliferation and survival [46]

however, the glycolytic flux must be kept in check in case of glucose deprivation (a scenario with inner-sphere cells of solid tumors)

The CD4 + regulatory T-cell (T reg ) subset primarily prevents a response to self-antigens and suppresses detrimental immune responses

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For instance, the immunostimulatory and epithelial cell-stimulating actions of azithromycin involve interactions between phospholipids and Erk1/2, as well as NF-B regulation

There is a clear and proven link between vitamin B12 deficiency and peripheral neuropathy