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Formalin administration may lead to an increase of NO which in turn would lead to formation of cyclic guanosine monophosphate (cGMP) by activation of guanylyl cyclase

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The combination of tert -butyl hydroperoxide and poly(bis-1,2-phenyl)diselenide was the one that showed the best result: 90% yield after 12 h reaction and recrystallization (Table 3, entry 3)

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