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*Correspondence: Lu Luo, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Few studies suggest that IGF-1 is upregulated in damaged muscle tissue and is associated with chronic pain conditions such as endometriosis, bone cancer, and orofacial pain 20,21

10.1016/S1360-1385(01)01898-2 20 Correa-AragundeN.ForesiN.DelledonneM.LamattinaL

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Often referred to as the master antioxidant, glutathione is essential to protect all cells, tissues and organs form oxidative fallout and damage