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The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI
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WFKD can improve fasting blood glucose, insulin resistance, weight, and body composition in women with stage IV metastatic breast cancer
Given that nitroxyl reacts with thiol proteins, it may be predicted that nitroxyl treatment could lead to depletion of cellular GSH
10.1152/ajplegacy.1971.221.4.1038 188 KlauserR.PragerR.GaubeS.GisingerC.SchnackC.KuenburgE.et al (1991)
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