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In consequence, the molecule selected was ligand 356 due to its high affinity for MAO-A and low affinity energy for MAO-B, which suggests selective binding properties

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Similarly, an animal model of diabetes-induced HF showed altered expression levels of copper transporter proteins and disturbed copper metabolism in rat cardiomyocytes (67)

Or the participant might be on a medication that can react to the new drugs active ingredient which would also disqualify them